Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270392 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A Pd-catalyzed protocol has been developed for the synthesis of fused steroidal and non-steroidal pyrimidines from β-halo-α,β-unsaturated aldehydes under microwave irradiation. The β-halo-α,β-unsaturated aldehydes are synthesized from corresponding ketones using Vilsmeier formylation reaction. This synthetic protocol is utilized to synthesize some more novel steroidal pyrimidine derivatives and are currently being evaluated for their biological activities.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Junali Gogoi, Pranjal Gogoi, Pranjal Bezbaruah, Romesh C. Boruah,