Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270404 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
A new three-component cascade reaction for the synthesis of thiohydantoins is reported. The reaction between α-amino esters, nitrostyrenes, and aromatic isothiocyanates is efficiently promoted by organic bases to afford highly substituted thiohydantoins in moderate to good yields and diastereoselectivities.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Victor Ceban, Kane Hands, Marta Meazza, Mark E. Light, Ramon Rios,