| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270408 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
An efficient synthesis of chiral N-tert-butanesulfinyl trifluoromethyl ketimines by using zirconium(IV) tert-butoxide is described. Compared to conventional titanium(IV) ethoxide, this protocol gave better result especially for sterically hindered ketones. In addition to the high reactivity, a high degree of enantiopurity of the N-tert-butanesulfinyl group is retained.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Toshio Kawanami, Alexander S. Karns, Christopher M. Adams, Michael Serrano-Wu,