Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270444 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Ytterbium triflate was shown to be effective in promoting the synthesis of substituted indole derivatives starting from indole, aldehydes, and dimethyl malonate by a Yonemitsu-type three component reaction. The whole process was carried out in solvent-free conditions and furnished the desired adducts in 42-67% yield.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Francesco Epifano, Salvatore Genovese, Ornelio Rosati, Silvia Tagliapietra, Caroline Pelucchini, Massimo Curini,