| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270505 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
Hydroxytyrosol [1, 2-(3,4-dihydroxyphenyl)ethanol], an olive-derived potent natural antioxidant was conveniently prepared from the clove-derived and commercially available eugenol (8, 4-allyl-2-methoxyphenol) using inexpensive reagents in a two-pot four-step process, which successively encompasses a reductive ozonolysis into homovanillyl alcohol (4, 4-hydroxy-3-methoxyphenethanol) and a sodium periodate-mediated oxidative demethylation using a reductive workup.
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Related Topics
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Chemistry
Organic Chemistry
Authors
Denis Deffieux, Philippe Gossart, Stéphane Quideau,