Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270510 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
Efficient asymmetric Mannich addition reactions between α,β-unsaturated ketone derived enolates and N-phosphonyl imines were reported. These reactions could proceed smoothly for a variety of imine substrates with good (up to 96%) chemical yields and excellent diastereoselectivities (up to 98:2 dr). The method reported in this work provides an easy access to chiral βâ²-amino-α,β-enones.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yiwen Xiong, Haibo Mei, Jianlin Han, Guigen Li, Yi Pan,