Article ID Journal Published Year Pages File Type
5270552 Tetrahedron Letters 2009 5 Pages PDF
Abstract

DDQ-catalyzed oxidative cross-coupling reaction between indoles and propargyl compounds is reported for the first time. The reaction involves direct carbon-carbon bond formation between sp2 carbons of indoles and sp3 carbons of propargylates to yield the corresponding propargyl indoles in good yields with high selectivity.

Graphical abstractSynthesis of propargyl indoles has been accomplished by oxidative cross-coupling between propargylic sp3 and indole sp2 carbons using DDQ.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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