| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270632 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Attempts to prepare JNJ 26273364, a highly functionalized pyrazole-based CCK1 receptor antagonist, using a carboxylation reaction led to a series of unexpected results. This work demonstrated the unique reactivity and stability of the highly functionalized Z-alkene functionality present around the pyrazole.
Graphical abstractAttempts to prepare JNJ 26273364, a highly functionalized pyrazole-based CCK1 receptor antagonist, using a carboxylation reaction led to a series of unexpected results. This work demonstrated the unique reactivity and stability of the highly functionalized Z-alkene functionality present around the pyrazole.Download full-size image
Related Topics
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Authors
Laurent Gomez, Jiejun Wu, Neelakandha S. Mani, Sudip Basu, Josef Moravek, J. Guy Breitenbucher,