| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270695 | Tetrahedron Letters | 2014 | 5 Pages |
Abstract
â¢Direct foramidation procedure of electron rich aromatic halides was developed.â¢Aryl amination was performed on open air without copper ligand.â¢Economical approach to aryl C-N bond formation.â¢Copper(II) sulfate mediated reactions.
A simple synthetic procedure for direct formamidation and amination of aryl halides mediated by copper(II) salts was developed in open air, without an external ligand in formamide with potassium carbonate as a base. This approach is particularly efficient when electron active aryl halides are used as substrates. In these cases almost quantitative formamidation was observed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rajesh Komati, Branko S. Jursic,