Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270717 | Tetrahedron Letters | 2014 | 5 Pages |
Abstract
An efficient one-pot synthesis of 2-substituted quinoxalines from 1,2-diamines and phenacyl bromides is developed using K10-montmorillonite (K10 clay) as a catalyst at 50 °C in acetonitrile medium. This method offers an easy route for the synthesis of substituted quinoxalines in high yields. A plausible mechanism is proposed in which quinoxalines are formed via dehydration-dehydrohalogenation-cyclization sequence. Further, the K10 clay catalyst is recovered by simple filtration and reused six times without any loss in its catalytic activity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mariappan Jeganathan, Amarajothi Dhakshinamoorthy, Kasi Pitchumani,