An inexpensive cyclodiphosphazane as an efficient ligand for the palladium-catalyzed amination of aryl bromides and chlorides

An economic and novel ligand, cyclodiphosphazane [ClPN(t-Bu)]2 (1), was introduced in the palladium-catalyzed amination of unactivated aryl halides. The catalyst allows for the amination of aryl chlorides and bromides with secondary cyclic amines and anilines in good yields.

Graphical abstractA new catalytic system for the C–N bond formation between aryl bromides/chlorides with amines, using Pd2dba3 and an inexpensive cyclodiphosphazane (1) as a ligand, is presented.Figure optionsDownload full-size imageDownload as PowerPoint slide