Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270780 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A convenient one-pot synthesis of phenols to anilines using 2-chloroacetamide/K2CO3/DMF system catalyzed by KI via Smiles rearrangement has been described. The synthesis of extensive amino aromatic products from phenols containing electron withdrawing group, has been performed in moderate to excellent yields to demonstrate the potentiality of this method in bio-medicinal and pharmaceutical applications.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yong-Sheng Xie, B.V.D. Vijaykumar, Kiwan Jang, Hong-Hyun Shin, Hua Zuo, Dong-Soo Shin,