Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270905 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
A novel and practical method for the synthesis of diverse α-aryl and α-vinyl nitriles was developed via an iron-catalyzed sp3 C-O ether bond cleavage with C-C bond formation in the reaction of Ï-activated ethers with TMSCN.
Graphical abstractDirect cyanation of Ï-activated ethers to synthesis of α-aryl and α-vinyl nitriles via iron-catalyzed sp3 C-O ether bond cleavage was developed.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaohui Fan, Kun Guo, Yong-Hong Guan, Lin-An Fu, Xiao-Meng Cui, Hao Lv, Hong-Bo Zhu,