Article ID Journal Published Year Pages File Type
5270905 Tetrahedron Letters 2014 4 Pages PDF
Abstract

A novel and practical method for the synthesis of diverse α-aryl and α-vinyl nitriles was developed via an iron-catalyzed sp3 C-O ether bond cleavage with C-C bond formation in the reaction of π-activated ethers with TMSCN.

Graphical abstractDirect cyanation of π-activated ethers to synthesis of α-aryl and α-vinyl nitriles via iron-catalyzed sp3 C-O ether bond cleavage was developed.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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