Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271016 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A tandem process for the oxidative amidation of benzyl alcohols with amine hydrochloride salts has been developed using inexpensive Fe(NO3)3 as the catalyst, air and aqueous t-butyl hydroperoxide as oxidants. A wide range of benzamides have been synthesized under mild conditions. This greener amide formation method provides an economical and practical assess to benzamides from readily available and inexpensive starting materials.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Subhash Chandra Ghosh, Joyce S.Y. Ngiam, Abdul M. Seayad, Dang Thanh Tuan, Charles W. Johannes, Anqi Chen,