Article ID Journal Published Year Pages File Type
5271016 Tetrahedron Letters 2013 4 Pages PDF
Abstract

A tandem process for the oxidative amidation of benzyl alcohols with amine hydrochloride salts has been developed using inexpensive Fe(NO3)3 as the catalyst, air and aqueous t-butyl hydroperoxide as oxidants. A wide range of benzamides have been synthesized under mild conditions. This greener amide formation method provides an economical and practical assess to benzamides from readily available and inexpensive starting materials.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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