Article ID Journal Published Year Pages File Type
5271054 Tetrahedron Letters 2010 7 Pages PDF
Abstract

Stereocontrolled synthesis of substituted isonitriles from the Baylis-Hillman adducts of acrylates has been developed. Ugi reaction of these isonitriles with TMSN3, aliphatic amines, and aldehydes or ketone affords 1-substituted tetrazoles which have been demonstrated to be suitable substrates for producing tetrazolo-fused diazepinones.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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