| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271082 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
We present a versatile method for chemical conjugation of a dinucleotide cap analogue with a cell-penetrating peptide. The final coupling reaction is between an azide-modified peptide (MPS-N3)-a fragment that is responsible for transport of the conjugate through the cell membrane, with a biologically active compound-and an alkynylated cap structure, using the Cu(I)-catalyzed click reaction.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Karolina Piecyk, Marzena Jankowska-Anyszka,