| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271144 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
An efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via one-pot three-component condensation of carbonyl compounds, amines, and potassium hexacyanoferrate(II) in the presence of benzoyl chloride as a promoter. This protocol has the features of use of eco-friendly cyanide source, high yield, and simple work-up procedure.
Graphical abstractAn efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via one-pot three-component condensation of carbonyl compounds, amines, and potassium hexacyanoferrate(II) in the presence of benzoyl chloride as a promoter.Download full-size image
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zheng Li, Yuanhong Ma, Jun Xu, Jinghong Shi, Hongfang Cai,