Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271223 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
An efficient protocol to generate indolo[1,2-c]quinazolines from acyclic alkyne substrates by ZnBr2-promoted domino hydroamination-cyclization has been established. The dichotomous properties of zinc salts involving alkynophilicity and oxophilicity assure a one-pot formation of five- and six-membered nitrogen-containing rings in the skeleton.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Min Xu, Ke Xu, Shaozhong Wang, Zhu-Jun Yao,