| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271233 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
Dehydrative synthesis of oxazolidinones from amino alcohols and CO2 was achieved in the presence of alkali metal carbonates such as Cs2CO3 as catalyst. It is noteworthy that 1Â atm of CO2 is enough for the reaction to proceed and no special dehydrating agent is required in this system. A mechanstic study showed that the OH of amino alcohol acts as nucleophile and the OH in the carbamic acid moiety is liberated during the cyclization process.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Siong Wan Foo, Yuki Takada, Yusuke Yamazaki, Susumu Saito,