Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271272 | Tetrahedron Letters | 2009 | 5 Pages |
Here we demonstrate for the first time the synthesis of α-aminophosphonates through the three-component coupling reaction of aldehydes, amines, and diethyl phosphite by using highly acidic 3D mesoporous aluminosilicate nanocage catalyst, which gave excellent yield with a high selectivity in a short reaction time due to its high acidity, 3D pores, and a huge space in the nanocages.
Graphical abstractHere we demonstrate for the first time the synthesis of α-aminophosphonates through the three-component coupling reaction of aldehydes, amines, and diethyl phosphite by using highly acidic 3D mesoporous aluminosilicate nanocage catalyst, which gave excellent yield with a high selectivity in a short reaction time due to its high acidity, 3D pores, and a huge space in the nanocages.Download full-size image