Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271379 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Functionalization reactions of 1-alkynylimidazoles involving the formation of their 2-lithio derivatives followed by addition of various electrophiles are presented. This allows access to previously unreported 1,2-dialkynylimidazoles via 1-alkynyl-2-iodoimidazoles. The use of an aldehyde or sulfonimine electrophiles allows the direct formation of bicyclic ring systems.
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