Article ID Journal Published Year Pages File Type
5271436 Tetrahedron Letters 2010 4 Pages PDF
Abstract
The synthesis of various types of optically active α-(allenylsilane-containing)glycines via a chirality-transferring ester-enolate Claisen rearrangement of α-acyloxy-α-alkynylsilanes is described. The conversion of the rearranged products into the optically active silicon-free α-(allenyl)- and α-substituted-α-(allenyl)glycines was achieved by the removal of the Me2PhSi- or TMS group from the allene terminus.
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Physical Sciences and Engineering Chemistry Organic Chemistry
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