| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271439 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Fluorescein mercury acetate (FMA) derivative can be used as a chemosensor for NADH that plays key roles in cellular energy metabolism and dehydrogenase enzymatic reactions. The sensor recognizes NADH by two mercury metal ions in the compound using the metal-anion interaction and its subsequent binding-induced fluorescence changes of FMA. The FMA can detect an aqueous NADH concentration of approximately 1.0 μM and has a high selectivity over various anions including NAD+, the oxidized form of NADH.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sang Oh Jung, Ji Yeon Ahn, Sudeok Kim, Sujung Yi, Mi Hee Kim, Hyun Hye Jang, Seong Hyeok Seo, Min Sik Eom, Seung Kyung Kim, De Hun Ryu, Suk-Kyu Chang, Min Su Han,