Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271456 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
The LBAs (Lewis acid-assisted Brønsted acid catalysis) is proposed as possible mechanistic process in the simple FeCl3-catalyzed Michael reactions of chalcones with active methylene compounds in organic solvents. And iron salts were found to be effective promoters in the asymmetric Michael addition of 4-hydroxycoumarin to α,β-unsaturated ketone, which resulted in excellent yield and high level of enantioselectivity (up to 91% ee) in the presence of low catalytic amount of iron and simple chiral primary amine.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hua-Meng Yang, Yue-Hua Gao, Li Li, Zhen-Yu Jiang, Guo-Qiao Lai, Chun-Gu Xia, Li-Wen Xu,