Article ID Journal Published Year Pages File Type
5271484 Tetrahedron Letters 2013 5 Pages PDF
Abstract

The Ugi-4C reaction employing Nβ-protected-amino alkyl isonitrile, amino acid ester, aldehyde, and glycosyl acid has resulted in novel glycosylated peptidomimetics. The extension of MCR products for the synthesis of N,N′-orthogonally protected glycosylated peptidomimetics has also been demonstrated.

Graphical abstractUgi-4C reaction employing Nβ-protected-amino alkyl isonitrile, amino acid ester, aldehyde, and glycosyl acid has resulted in novel glycosylated peptidomimetics. Further, the protocol has been extended for the synthesis of N,N′-orthogonally protected glycosylated peptidomimetics as well.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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