Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271514 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Lactols and their ethers undergo smooth allylation with allyltrimethylsilane in the presence of 5 mol % iodine in dichloromethane at â78 °C to afford C-allylfuranosides in good yields and with high diastereoselectivity. The use of iodine makes this method simple, convenient and practical. This is the first report on the allylation of lactols with allyltrimethylsilane using molecular iodine as a catalyst. Enhanced diastereoselectivity is the key feature of this protocol.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, B.V. Subba Reddy, A. Srinivas Reddy, Ch. Suresh Reddy, S. Satyanarayana Raju,