Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271556 | Tetrahedron Letters | 2013 | 4 Pages |
C3v-Symmetric tripodal anion receptors with three urea or thiourea recognition motifs were synthesized from C3v-symmetric cis,cis,cis-2,5,9-tri-p-bromobenzyltrindane molecular skeleton via Hartwig amination and then formation of urea compounds with the corresponding isocyanate. The anion receptors recognized halide and oxo anions with C3-symmetry through the hydrogen bonding interactions between anions and the NH protons of urea or thiourea groups. The receptors 2 and 3 showed a significant binding affinity toward H2PO4- in DMSO-d6; 392 and 305Â Mâ1, respectively. The strong affinity of H2PO4- anion may be attributed to its tetrahedral geometry and the basicity of H2PO4- anion, allowing it to form stronger hydrogen-bonding.
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