| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271588 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
The enantioselective Kinugasa reaction of nitrones with terminal alkynes in the presence of 20 mol % of IndaBox-Cu(OTf)2 and di-sec-butylamine (1.5 equiv) produced β-lactams with the highest level of enantiomeric excesses among the catalytic enantioselective Kinugasa reactions reported so far.
Graphical abstractThe highest level of enantioselectivity (79-94% ees) was attained in the catalytic Kinugasa reaction using the Cu(OTf)2-IndaBox complex.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Takao Saito, Tomohiro Kikuchi, Hiroaki Tanabe, Junichi Yahiro, Takashi Otani,