Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271602 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A highly enantioselective organocatalytic fluoromalonate addition to α,β-unsaturated aldehydes is reported. The reaction is catalyzed by simple and commercially available secondary amines, affording the corresponding 1,4-adducts with high yields and enantioselectivities.
Graphical abstractA highly enantioselective organocatalytic fluoromalonate addition to α,β-unsaturated aldehydes is reported. The reaction is catalyzed by simple and commercially available secondary amines, affording the corresponding 1,4-adducts with high yields and enantioselectivities.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xavier Companyó, Monika Hejnová, Martin Kamlar, Jan Vesely, Albert Moyano, Ramon Rios,