Article ID Journal Published Year Pages File Type
5271697 Tetrahedron Letters 2013 4 Pages PDF
Abstract

A series of novel spiro-2-amino-3-phenylsulfonyl-4H-pyran derivatives were synthesized via the three component, one pot reaction of phenylsulfonylacetonitrile and 1,3-dicarbonyl compounds with isatins or acenaphthenequinone in ethanol with a novel basic ionic liquid 2-hydroxyethyl ammonium acetate [H3N+CH2CH2OH][CH3COO−] (HEAA) as catalyst. HEAA was found to be a suitable and efficient catalyst for this condensation. This method has some distinct advantages such as mild reaction conditions, short reaction time, and environmental friendliness.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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