Article ID Journal Published Year Pages File Type
5271699 Tetrahedron Letters 2013 4 Pages PDF
Abstract

An efficient reaction protocol for the palladium-catalyzed synthesis of 2,4-diacetoxycyclopentylideneacetates by a reaction of acetic acid with 3,6-heptadienoic esters, has been developed. The process, which occurs in the presence of oxidants, represents the first example of sequential double acetoxylation-cyclization of substituted 1,4-dienes to form cyclopentane rings with oxygen functionalities at 2 and 4 carbon atoms. The use of a water/acetic acid reaction medium has also been shown to give satisfactory results.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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