| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271713 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
Tin-free, photoinduced electron transfer promoted reductive radical cyclization reactions of allyl 2-bromoaryl ethers in the presence of NaOH in 2-PrOH were found to take place efficiently to give 3-methyl-2,3-dihydrobenzofurans. In contrast to conventional radical cyclization reactions that employ AIBN/Bu3SnH in benzene, the new method utilizes NaOH and 2-PrOH that are both readily available and benign. Consequently, the newly developed photochemical process serves as a versatile and environmentally friendly method for carrying out aryl radical cyclization reactions.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yasuharu Yoshimi, Hirotomo Kanai, Keisuke Nishikawa, Yasushi Ohta, Yoshiki Okita, Kousuke Maeda, Toshio Morita,