Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271750 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
Depending on their relative orientation, coupled oscillating carbonyl groups provide a VCD spectrum with a characteristic CO bond stretching region showing a strong bisignate VCD feature, which can be readily predicted adopting long available semiempirical methods. The extended coupled oscillator (ECO) formalism has been used to assign the absolute configuration of a recently synthesized chiral 3-substituted isoindolinone. The prediction of (S) configuration for the (â) enantiomer has been confirmed by quantum mechanical calculations.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Antonio Massa, Paola Rizzo, Guglielmo Monaco, Riccardo Zanasi,