| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271769 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Novel α-carboranyl-α-acyloxy-amides were prepared as potential BNCT agents utilizing three-component Passerini reaction. Preliminary cytotoxicity of the representative compounds on two brain tumor cell lines (U-87 and A-172) showed no effect on cell viability; an essential requirement for utility as potential BNCT agents.
Graphical abstractNovel α-carboranyl-α-acyloxy-amides were prepared as potential BNCT agents utilizing three-component Passerini reaction. Preliminary cytotoxicity of the representative compounds on two brain tumor cell lines (U-87 and A-172) showed no effect on cell viability; an essential requirement for utility as potential BNCT agents.Download full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Subash C. Jonnalagadda, Jonathan S. Cruz, Ryan J. Connell, Patricia M. Scott, Venkatram R. Mereddy,