Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5271774 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
An efficient method for chemoenzymatic dynamic kinetic resolution of selenium-containing chiral amines (organoselenium-1-phenylethanamines) has been developed, leading to the corresponding amides in excellent enantioselectivities and high isolated yields. This one-pot procedure employs two different types of catalysts: Pd on barium sulphate (Pd/BaSO4) as racemization catalyst and lipase (CAL-B) as the resolution catalyst.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Leandro H. Andrade, Alexandre V. Silva, Eliane C. Pedrozo,