Article ID Journal Published Year Pages File Type
5271780 Tetrahedron Letters 2009 4 Pages PDF
Abstract

Novel sulfur-linked squaryl group-containing glutamate analogs were synthesized via addition and mono-substitution reactions of thiols to t-butyl methyl squarate (BMSQ: 7) in two steps. A glutamate analog prepared from Boc-l-Cys showed a potent binding affinity to KA/AMPA receptors.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry