| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271858 | Tetrahedron Letters | 2009 | 5 Pages |
Abstract
The intramolecular cyclization of amidoalkyl naphthols by Vilsmeier reagent produced 1,3-oxazines. The Vilsmeier reagent (chloromethylenedimethylammonium chloride) has been used as an efficient and cheap acid activator for the one-step synthesis of oxazine derivatives. A mechanism involving sequential haloformylation and intramolecular nucleophilic cyclization is proposed.
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Authors
M. Damodiran, N. Panneer Selvam, Paramasivan T. Perumal,