Article ID Journal Published Year Pages File Type
5271945 Tetrahedron Letters 2010 4 Pages PDF
Abstract

Several polymeric supports possessing an ester moiety were prepared and a range of enzymes was investigated to hydrolyse the ester linkage and release a signalling group into solution for applications in immunoassays. Pseudomonas lipases were found to most readily cleave the solution-phase analogue and this observation translated well to the corresponding polymeric supports, where the most effective were PEGA resins and the LPOS support PEG-6000.

Graphical abstractA range of polymeric supports was prepared and investigated for applications in an enzyme cleavable assay.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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