| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5271950 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Synthesis of trifunctional thiourea catalysts tethered with a variety of functional group is described. 1,5-Triazole tether in the catalysts was constructed by ruthenium-catalyzed Huisgen cycloaddition. We demonstrate the utility of the synthetic thioureas as an asymmetric catalyst for Michal addition of nitrostyrene with cyclohexanone.
Graphical abstractSynthesis of trifunctional thiourea catalysts tethered with a variety of functional group is described. 1,5-Triazole tether in the catalysts was constructed by ruthenium-catalyzed Huisgen cycloaddition. We demonstrate the utility of the synthetic thioureas as an asymmetric catalyst for Michal addition of nitrostyrene with cyclohexanone.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kiyosei Takasu, Takumi Azuma, Yoshiji Takemoto,