Article ID Journal Published Year Pages File Type
5271956 Tetrahedron Letters 2010 4 Pages PDF
Abstract

Conditions for a FeCl3/PPh3-catalyzed and palladium-, copper-, amine free-Sonogashira coupling reaction of aryl halides with terminal alkynes are reported. The protocol was applicable to a wide variety of substituted aryl iodides and alkynes with different steric and electronic properties and gave excellent yields of the desired coupling products.

Graphical abstractConditions for a FeCl3/PPh3-catalyzed and palladium-, copper-, amine free-Sonogashira coupling reaction of aryl halides with terminal alkynes are reported.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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