| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272057 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
We report an efficient one-step route to 2-fluoroalkylbenzimidazoles and -benzothiazoles via the condensation of fluorinated carboxylic acids and aromatic diamines or aminothiophenols. Additionally, we describe the syntheses of fluoroalkyl-azabenzimidazoles, -purines, and -imidazolopyrazines. This method is high-yielding with broad scope and is operationally simple with potential application to parallel synthesis.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Olivier René, Alexandra Souverneva, Steven R. Magnuson, Benjamin P. Fauber,