Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272124 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A simple and efficient synthesis of α-aminophosphonates has been developed via the one-pot three-component reactions of aldehydes, amines, and trialkyl phosphites. The reactions occurred rapidly at room temperature in the presence of 1 equiv of propylphosphonic anhydride (T3P®) as the condensing agent, and the α-aminophosphonate products were obtained in high yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mátyás Milen, Péter Ábrányi-Balogh, András Dancsó, Dávid Frigyes, László Pongó, György Keglevich,