Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272174 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Methodology to rapidly and efficiently assemble 8-trifluoromethyltetrahydro-6H-pyrido [1,2-a] pyrazine-6-one (11) has been developed and its general applicability has been demonstrated.
Graphical abstractA cascade cyclization approach to afford pyrazine-one (11) from ynoate (12) is discussed.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shankaran Kothandaraman, Deodialsingh Guiadeen, Gabor Butora, George Doss, Sander G. Mills, Malcolm MacCoss, Lihu Yang,