| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272175 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
This Letter reports on the novel use of n-butylisonitrile as a cheaper, more atom economical alternative to currently reported 'designer' convertible isonitriles in UDC (Ugi/DeProtect/Cyclize) methodology. Transformations to diketopiperazines and 1,4-benzodiazepine-2,5-diones are facilitated by microwave irradiation and proceed in excellent yield.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Christopher Hulme, Shashi Chappeta, Justin Dietrich,