| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272183 | Tetrahedron Letters | 2009 | 5 Pages |
Abstract
The monodentate ligand 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha-adamantane (PA-Ph) is shown to be highly effective in palladium-catalyzed carbonylative cross-coupling. Aryl and vinyl halides were efficiently converted to carboxylic acids, amides and to primary, secondary, and tertiary esters, respectively. Application of the Pd(OAc)2/PA-Ph (1:1) catalyst system proved critical in the methoxycarbonylation of a functionalized nitroresorcinol halide, allowing convenient access to novel platensimycin sulfonamide analogs.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
James McNulty, Jerald J. Nair, Alfredo Capretta,