| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272191 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A stereoselective synthesis of potent cytotoxic macrolides, 11-α-methoxycurvularin and 11-β-methoxycurvularin has been accomplished. The synthesis entailed Maruoka asymmetric allylation to introduce the stereocentres at C-11 and the key fragment was installed by using Grubbs cross-metathesis followed by CBS-reduction.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
G. Venkateswar Reddy, R. Sateesh Chandra Kumar, K. Suresh Babu, J. Madhusudana Rao,