| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5272267 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
An efficient method for a stereoselective synthesis of optically pure N-Boc-3-arylpiperazines has been developed. After optimization of the protecting group strategy and experimental conditions, compounds were obtained via a highly stereoselective synthesis in up to 45% overall yield. This is a practical route to optically pure piperazines for medicinal chemistry.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mouhamad Jida, Guillaume Laconde, Olivier-Mohamad Soueidan, Nicolas Lebegue, Germain Revelant, Lydie Pelinski, Francine Agbossou-Niedercorn, Benoit Deprez, Rebecca Deprez-Poulain,