Article ID Journal Published Year Pages File Type
5272324 Tetrahedron Letters 2009 4 Pages PDF
Abstract

A convenient way for the synthesis of acylsilanes from arabinose, lyxose, and ribose is developed. All the chiral centers of the carbohydrate templates are conserved, and only the reducing end is transformed into the acylsilane functional group. The non-reducing end of the templates can be converted into a bromide. These bromo acylsilanes undergo efficient intramolecular radical cyclizations to give polyoxygenated cyclopentanes.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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