Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272324 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A convenient way for the synthesis of acylsilanes from arabinose, lyxose, and ribose is developed. All the chiral centers of the carbohydrate templates are conserved, and only the reducing end is transformed into the acylsilane functional group. The non-reducing end of the templates can be converted into a bromide. These bromo acylsilanes undergo efficient intramolecular radical cyclizations to give polyoxygenated cyclopentanes.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Che-Chien Chang, Yu-Hsien Kuo, Yeun-Min Tsai,