Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272408 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A novel, efficient, and operationally simple one-pot synthesis of both, symmetrical and unsymmetrical N-acylureas from carboxamides and in situ generated isocyanates (from N,N-dibromo-p-toluenesulfonamide) in the presence of a mild base at rt is reported. The protocol avoids the tedious isolation and purification steps of hazardous isocyanates. The first application of these acylureas to the catalysis through hydrogen bonding is also demonstrated.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Atul K. Singh, Ruchi Chawla, Lal Dhar S. Yadav,