Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5272464 | Tetrahedron Letters | 2019 | 5 Pages |
Abstract
A phytochemical investigation of Isodon pharicus led to the isolation of a novel asymmetric ent-kauranoid dimer, bispseurata F (1), and three new diterpenoids pharicinins A-C (2-4). Their structures were elucidated by extensive spectroscopic analysis. Compound 1 features a unique linkage pattern of C-17 with C-11â² to connect the two monomers. A possible biogenetic pathway of 1 was also proposed. Compounds 3 and 4 exhibited moderate inhibitory activity against NB4 and SH-SY5Y cell lines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yong Zhao, Sheng-Xiong Huang, Wei-Lie Xiao, Li-Sheng Ding, Jian-Xin Pu, Xian Li, Li-Bin Yang, Han-Dong Sun,